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NeuralCloud and Etisense Agree to Explore MaxYield ECG Integration for Animal Research

AI/ML Innovations subsidiary NeuralCloud Solutions has entered an agreement with Etisense to assess the use of MaxYield for animal-model ECG analysis in preclinical research.

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AI/ML Innovations Inc. said its wholly owned subsidiary, NeuralCloud Solutions Inc., has entered into an agreement with Etisense SAS to assess the use of MaxYield™ for animal-model ECG labelling and analysis within Etisense’s LASA software. The agreement is dated October 27, 2026, and was announced on October 29, 2026.

#Validation will precede any wider integration

Under the arrangement, NeuralCloud will first conduct a validation stage using representative ECG files at no charge to Etisense. Progression beyond validation is subject to Etisense’s written approval.

The parties expect validation to be followed by technical work connecting MaxYield™ with the LASA workflow and then by online licensing for continued customer use. The agreement does not make those later stages certain. AI/ML Innovations identified possible validation shortfalls, a decision by Etisense not to proceed, technical and integration issues, and the potential termination or non-renewal of an online licence on 30 days' notice among the relevant risks.

#Initial focus on large-animal ECG data

The initial work is intended to cover large-animal models, including canine, porcine and primate models. Following validation of large-animal performance, the companies intend to evaluate whether the work can extend to small-animal models, including mouse and rat models.

NeuralCloud will supply the MaxYield™ signal-processing and labelling engine. Etisense will continue to manage its customer relationships, platform workflow and final review process. The agreement is non-exclusive, and NeuralCloud retains all intellectual property rights in MaxYield™.

#Roles of MaxYield and Etisense technology

MaxYield™ is described as NeuralCloud’s proprietary ECG processing technology. Its functions include improving signal clarity, identifying and labelling waveform components, calculating ECG intervals, detecting fiducial points and producing structured data for further analysis.

Etisense’s DECRO® system captures ECG, respiratory-function and locomotor-activity data from conscious, freely moving models without implant surgery. Its LASA software processes and analyses data from DECRO® and other third-party telemetry systems. In the proposed collaboration, MaxYield™ would operate as an additional ECG labelling and analysis layer within that existing workflow.

#Preclinical research scope and regulatory status

The companies are targeting workflows used by researchers, laboratories, contract research organisations and pharmaceutical partners conducting preclinical studies. The release describes potential applications in pharmacology, safety-toxicology, disease-model research and laboratory animal monitoring.

MaxYield™ has not received FDA or Health Canada clearance, authorisation or approval for clinical or diagnostic use. The current work with Etisense is limited to animal-model ECG labelling and preclinical research workflows. Any future regulated clinical or diagnostic use of MaxYield™ or related NeuralCloud products would be subject to applicable regulatory requirements, validation and approvals.

#Risks and remaining conditions

AI/ML Innovations said the arrangement is subject to uncertainties involving validation results, Etisense’s approval to move forward, technical performance, integration, competition, market acceptance, regulatory review and applicable approvals. The company also identified uncertainty around end-customer adoption and related subscription revenue. Further terms and conditions apply to the transaction beyond those set out here.

AI/ML Innovations shares trade under CSE:AIML, OTCQB:AIMLF and FWB:42FB.

#Key Takeaways

  • NeuralCloud Solutions entered an agreement dated October 27, 2026, with Etisense to assess MaxYield™ within the LASA software workflow.
  • The first stage involves no-charge validation using representative ECG files, and further progress requires Etisense’s written approval.
  • Initial testing is focused on canine, porcine and primate models, with mouse and rat models to be evaluated after large-animal validation.
  • The agreement is non-exclusive, while NeuralCloud retains MaxYield™ intellectual property rights and Etisense keeps responsibility for customer relationships and final review.
  • MaxYield™ has not received FDA or Health Canada clearance, authorisation or approval for clinical or diagnostic use.

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