Healthcare

HSPO Announces Definitive Business Combination Agreement with ArcheNova Biotech

Horizon Space Acquisition I Corp. and ArcheNova Biotech Corp. have entered into a definitive business combination agreement, with completion subject to approvals and other closing conditions.

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Horizon Space Acquisition I Corp. and clinical-stage biopharmaceutical company ArcheNova Biotech Corp. announced a definitive business combination agreement on October 13, 2026. If the proposed transactions are completed, a newly formed Cayman Islands company named ArcheNova Technology Co., Ltd would become the parent company and is expected to be listed on The Nasdaq Stock Market LLC.

#Transaction remains subject to approvals

The proposed combination has been approved unanimously by the boards of directors of HSPO and ArcheNova. Closing is subject to regulatory and shareholder approvals, along with other customary closing conditions.

The companies currently expect the transaction to close in the first quarter of 2027. They stated that there is no assurance the proposed transactions will be completed on the terms or timetable currently contemplated, or at all.

#Planned transaction structure

Under the agreement, ArcheNova International Co., Ltd would merge with and into HSPO. HSPO would remain as the surviving entity and become a wholly owned subsidiary of the new parent company.

In a subsequent step, ArcheNova Global Co., Ltd would merge with and into ArcheNova Biotech Corp., with ArcheNova surviving as another wholly owned subsidiary of the parent company.

After completion, shareholders of HSPO and ArcheNova would receive ordinary shares of ArcheNova Technology Co., Ltd as consideration. HSPO warrants would be assumed by the parent company and converted into warrants exercisable for its ordinary shares on substantially the same terms and conditions. The parent company's ordinary shares are expected to be listed and traded on Nasdaq following consummation of the proposed transactions, subject to the applicable conditions, including the ability to obtain or maintain that listing.

Upon completion of the proposed transaction, ArcheNova Technology Co., Ltd will be led by Dr. Lim Sai Kiang as Chief Executive Officer and Chief Scientist. Liu Ye is expected to serve as Chief Financial Officer.

#ArcheNova's drug development platform

ArcheNova describes itself as a clinical-stage, platform-based biopharmaceutical company working on medicines derived from mesenchymal stromal cell-derived extracellular vesicles and exosomes. Its activities include research, development, clinical translation, scalable manufacturing and global commercialization.

The company's platform uses an immortalized monoclonal mesenchymal stromal cell producer line, a good manufacturing practice master cell bank, controlled production processes and an integrated chemistry, manufacturing and controls framework. ArcheNova says the approach is intended to provide a defined biological source for exosome production and to support shared manufacturing and quality systems across different medical indications.

ArcheNova is advancing five product candidates across dermatology, orthopedics, ophthalmology, neurology and cardiology. The programs are at different stages of development.

#Psoriasis program advances toward Phase II

ArcheNova's lead topical psoriasis program has completed a Phase I clinical trial involving ten healthy volunteers at Singapore's National University Hospital. The company is preparing the program for Phase II clinical evaluation.

#Regulatory filings and next steps

HSPO, ArcheNova and the proposed parent company intend to file a registration statement on Form F-4 with the Securities and Exchange Commission. The filing is expected to include a proxy statement for HSPO shareholders and a prospectus covering the ordinary shares of the parent company to be issued in the proposed transactions.

HSPO also plans to provide additional transaction information, including a copy of the business combination agreement, in a Current Report on Form 8-K filed with the SEC. A definitive proxy statement/prospectus, if and when available, will be delivered to HSPO shareholders. Further transaction terms and conditions apply beyond those set out here.

#Key Takeaways

  • HSPO and ArcheNova have entered into a definitive business combination agreement.
  • The proposed transactions could create a new parent company, ArcheNova Technology Co., Ltd, with a planned Nasdaq listing upon completion.
  • Closing is currently expected in the first quarter of 2027, subject to regulatory and shareholder approvals and other customary closing conditions.
  • ArcheNova is advancing five product candidates across dermatology, orthopedics, ophthalmology, neurology and cardiology.
  • Its lead topical psoriasis program completed Phase I in ten healthy volunteers and is being prepared for Phase II clinical evaluation.

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